Some of the document and global settings you may want to change:
- Margins
- Grids/Columns
- Gutters/Column spacing
- Fonts
- Leading
- Tabs/Paragraph indents
- Paragraph spacing
- Drop cap settings
- Text wrap offsets
- Page size and Orientation
- Placement and Color of Guides
- Measurements and ruler settings
- Graphic display
- Text display
- Automatic typographer's marks, error correction, hyphenation
- Character styles
- Paragraph styles
Default settings are not inherently right or wrong. They are great for getting you started faster but don't forget to fine-tune those settings to meet the needs of the particular type of document you are creating.