Are you a new Mac user? Even if you've been with Apple since 1984 chances are you haven't tried every possible Mac app out there. If you're looking for a real workhorse but don't want to go through the hassle of trying out dozens of programs, start with what some of my fellow Guides are using. About.com Macs Guide Tom Nelson has a round-up of must-have Mac software from Jennifer Krynin, About.com Guide to Web Design (Pages and Photoshop for two), Shelley Elmblad, About.com Guide to Financial Software (OpenOffice, among others), Dixie Allen, About.com Guide to Clip Art (InDesign and Office for Mac are on the list), and several other Guides. See what they're using and why.
Also see: Mac Desktop Publishing Software | Mac Professional Software | Free Mac Software